The recent ascendancy of competitive nationalism and populist politics in the United States and Europe has greatly increased uncertainty for business—developed markets and large emerging markets can no longer be considered benign and predictable from a political risk perspective, and business can no longer assume a steady journey toward ever-greater economic liberalization and regulatory convergence. At the same time, public trust in business has collapsed. Participants in this timely, in-depth discussion will learn how to respond to external developments and reputational concerns on a much more coordinated, real-time basis, and how a focus on stakeholder trust can lead to long-term company sustainability.