For the past half-century, the approach to transportation infrastructure—rail, road, air, and sea—has remained essentially the same. However, the convergence of technological innovation and an increase in needed infrastructure investment have created a unique opportunity to think differently. Our traditional road, rail, and airline systems could be replaced with something straight out of a science fiction movie. This cutting-edge conversation will explore how alternative high speed rail, driverless cars, the commercialization of space travel, drone delivery of packages, and other innovations could fundamentally change transportation and logistics as we know it, and the resulting sustainability impacts and benefits that could come with the systemic shift.